Research highlights
Clinical trials published in peer-reviewed medical journals demonstrate that visual diagnostic screening tools maintain high sensitivity for early detection of diabetic neuropathy.
Key clinical findings across international studies show:
- High diagnostic sensitivity when compared against complex nerve conduction velocity testing.
- Effective identification of patients at high risk of developing future foot ulcers.
- Excellent patient preference scores due to the painless nature and ease of use of the test.

Key clinical studies
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Autonomic neuropathic symptoms in patients with diabetes: practical tools for screening in daily routine
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Validation of Neuropad in the Assessment of Peripheral Diabetic Neuropathy in Patients with Diabetes Mellitus Versus the Michigan Neuropathy Screening Instrument, 10g Monofilament Application and Biothesiometer Measurement.
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Automated quantification of Neuropad improves its diagnostic ability in patients with diabetic neuropathy.
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The diagnostic accuracy of Neuropad for assessing large and small fibre diabetic neuropathy.
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The indicator test Neuropad in the assessment of small and overall nerve fibre dysfunction in patients with type 2 diabetes: a large multicentre study.
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A simple plaster for screening for diabetic neuropathy: a diagnostic test accuracy systematic review and meta-analysis.
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Influence of peripheral arterial occlusive disease on the Neuropad test performance in patients with diabetes.
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A simple new non-invasive sweat indicator test for the diagnosis of diabetic neuropathy.
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Useful application of the Neuropad test for assessment of diabetic polyneuropathy.
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Evaluation of the Neuropad sudomotor function test as a screening tool for polyneuropathy in the elderly population with diabetes and pre-diabetes: the KORA F4 survey.
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The diagnostic value of water immersion skin wrinkling and Neuropads in small fiber neuropathy.
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Neuropad: evaluation of three cut-off points of sudomotor dysfunction for early detection of polyneuropathy in recently diagnosed diabetes.
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Accuracy of the Neuropad test for the diagnosis of distal symmetric polyneuropathy in type 2 diabetes.
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A prospective study on the use of the indicator test Neuropad for the early diagnosis of peripheral neuropathy in type 2 diabetes.
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Diagnosis of diabetic neuropathy using simple somatic and a new autonomic (Neuropad) tests in the clinical practice.
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Moisture status of the skin of the feet assessed by the visual test Neuropad correlates with foot ulceration in diabetes.

